Online NFL betting sites grants bettors from across the globe access to NFL betting wagering on other sports, but we will look at football specifically for this guide. while watching a game, live betting has become more and more popular. NFL Vegas Odds, Betting Lines, and Point Spreads provided by VegasInsider. com, along with more pro football information for your sports gaming and betting needs. Open Line: Consists of the first betting line received from one of our Las Vegas or Online sportsbooks. All Game Times are Eastern Standard Time. Get the latest up to date NFL Full Odds, Offshore and Vegas odds, spreads, line moves and totals for all pro NFL Football Full Live Odds & Betting Lines.